One Health One Omics Workshop
Date: Sunday 17th September 2017
Location: O’Brien Centre for Science, University College Dublin
Chairs: Paola Roncada & Subhra Chakraborty
Subhra Chakraborty, NIPGR, INDIA; Paola Roncada, Istituto Spallanzani, Italy; Emoke Bendixen, Aarhus University, Denmark; Stephen Pennington, University College Dublin, Ireland and Stephen Gordon, University College Dublin, Ireland
One Health is an holistic approach that combines several biological disciplines to examine the relationships between human, plant and animal health care. One Health research focuses on diverse biomolecules and seeks to combine data from genomics, transcriptomics, proteomics, epigenomics, metabolomics and microbiomics. So, although enormous possibilities lie in this multi-omics approach translating the individual findings to utility for healthcare is still in its infancy.
The One Health concept calls for a paradigm shift to understand the interactions between plants, animals, humans, and the environment and how these interactions affect the human health, food security and safety under changing climatic conditions. This ‘One Health’ approach is vital because 6 out of every 10 infectious diseases in humans are spread from animals and around 7% of emerging pathogens (Ebola, West Nile, Avian, Influenza) are transmitted from animals to humans. It is also estimated that 1 in 6 people in the USA become sick due to a foodborne illness at an estimated annual econocic cost of $77 billion each year (https://www.cdc.gov/onehealth/index.html).
As all life forms are connected, understanding the interactions between them is critical to protecting the health of all.
13.00-13.30 Professor Steve Gordon:
Introduction to One Health One Omics
13.30-13.45 Professor Subhra Chakraborty
Dynamic plant proteomes: towards food, health and nutritional security
13.45-14.00 Professor Paola Roncada
Zoonoses explored by proteomics: experience from the ERA NET – ArimMNET2
14.00-14.10 Sanjeeva Srivastava: Biomarkers for vivax malaria
14:10-14:20 Da Qi: Rice genome annotation
14:20-14:30 Christian Seeger: Proteomic analysis of Lactobacillus kunkeei
14:30-14:40 Cristian Piras: Peptidomics characterization of allergenic and non-allergenic protein orthologs.
Tea/Coffee Break: 14:40-15:00
Panel discussion & Recommendations:
Moderators: Subhra Chakraborty & Paola Roncada
Panelists: Steve Gordon, Emoke Bendixen, David Goodlet, Ileana Cristea, Daniel Figeys,
Through a lively panel discussion we will seek to understand and identify challenges, opportunities and strategy in the field of One Health by bringing together individuals and organizations from diverse sectors to discuss key questions. In so doing we aim to increase a shared awareness that will advance healthcare for the 21st century and beyond.
Examples of Key Questions:
• How to converge human, animal and plant health and the health of the environment?
• In what ways does proteomic research tangibly contribute to a One Health approach to the benefit human health and food security?
• How can the study of proteomes of model organisms impact on to precision medicine?
• What is meant by precision agriculture? What impact will it have?
• How can proteomics contribute to improved food safety issues?
• What is the role of industry in supporting/contributing to proteomics for One Health: What industries? Crop, farm animal, food, bakery, brewery or other?
• Are newer and/or more specialised methods and approaches required to support the development of One Health proteomics?
Registration Fee: Euro 45 per person